When choosing a motherboard, size matters! Micro ATX (mATX) is the most compact option, ideal for smaller cases and budget builds. It offers less space for features, typically having fewer expansion slots and RAM slots. ATX, the most popular size, strikes a balance between size and features, suitable for most users. Finally, EATX motherboards are the biggest and beefiest. They boast the most space for high-end components like multiple graphics cards and tons of RAM, but require large cases and are pricier.